General Information

  • ID:  hor004270
  • Uniprot ID:  Q76LC8
  • Protein name:  Tachykinin-related peptide
  • Gene name:  Ptk
  • Organism:  Procambarus clarkii (Red swamp crayfish)
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Procambarus (genus), Cambarinae (subfamily), Cambaridae (family), Astacoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  APSGFLGMR
  • Length:  9
  • Propeptide:  MVRGAAIGLMVMVVVTGALAEEQDTADRERRAPSGFLGMRGKKDVSTPLENIVPAVNDYTLQDSFPASLYGLRDDNGPVVLAVPWRVKKAPSGFLGMRGKKSGEEAFGEAGMDSELETLLKRAPSGFLGMRGKKAPSGFLGMRGKKAPSGFLGMRGKKHFDDESEIDAYIQALTAMVDGQQEKRAPSGFLGMRGKKAFFGDSSDEEMSVAGVDKRAPSGFLGMRG
  • Signal peptide:  MVRGAAIGLMVMVVVTGALA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  myoactive
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-Q76LC8-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004270_AF2.pdbhor004270_ESM.pdb

Physical Information

Mass: 107798 Formula: C41H66N12O11S
Absent amino acids: CDEHIKNQTVWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 3
Hydrophobicity: 28.89 Boman Index: -438
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 54.44
Instability Index: 4331.11 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  15066180
  • Title:  APSGFLGMRamide Is a Unique Tachykinin-Related Peptide in Crustaceans